'Molecular crowbar' protein degradation strategy offers new hope in cancer therapy
In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins. A University of California, Riverside team of scientists has used a novel approach to ...
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Protein Degradation Strategy Sparks Cancer Therapy Hope
Cancer-associated fibroblasts are cells that play a key role in the development and ... "Our molecular degrader, the 'crowbar ...
Scientists use microcellular drones to deliver lung cancer-killing drugs
In a study led by researchers at the NUS Yong Loo Lin School of Medicine, extracellular vesicles loaded with customizable ...
Research shows how even one faulty copy of the BRCA1 gene can fuel breast cancer
People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of ...
Pharmaceutical Technology3h
Autolus secures FDA approval for CAR-T cell therapy use in ALL
“Adult ALL is an extremely aggressive cancer, and there is a high unmet medical need that exists in the treatment of patients ...
Tumor suppressor forms gel-like assemblies to sacrifice cancer cells
There are processes in the human body that can suppress the growth and proliferation of cancer cells. These mechanisms, ...
Frontiers9h
Implications of Senescence in Cancer Immunology
However, research has demonstrated that senescent cells can also contribute to cancer development and progression. The tumor-suppressing and tumor-promoting activities are primarily attributable to ...
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Breast cancer awareness — a personal journey through early detection and treatment
I visualised the cluster of cells — an ominous, out-of-the-way gathering, deep in my breast, that I would never have known ...