In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins. A University of California, Riverside team of scientists has used a novel approach to ...

Cancer-associated fibroblasts are cells that play a key role in the development and ... "Our molecular degrader, the 'crowbar ...

In a study led by researchers at the NUS Yong Loo Lin School of Medicine, extracellular vesicles loaded with customizable ...

People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of ...

There are processes in the human body that can suppress the growth and proliferation of cancer cells. These mechanisms, ...

However, research has demonstrated that senescent cells can also contribute to cancer development and progression. The tumor-suppressing and tumor-promoting activities are primarily attributable to ...

Scientists have discovered a way to target elusive circular fragments of DNA that drive the survival of some of the most aggressive cancers, paving the way for future treatments.

The good news is that drugs called CHK1 inhibitors were found to selectively destroy tumor cells containing ecDNA in mice ...

Less frequent IV dosing with nemvaleukin in patients with select advanced solid tumors, including ovarian cancer and mucosal melanoma, showed ...

Unexpectedly, if this quality control is not followed, more MHC-I molecules may make it to the surface of cancer cells, ...

Adaptive Biotechnologies Corporation (Nasdaq: ADPT), a commercial stage biotechnology company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and ...