Two NFC West teams renew their rivalry as we continue our NFL odds series with a 49ers-Rams prediction and pick.

Like for many other head coaches and offensive coordinators across the NFL facing the Los Angeles Rams, life has gotten a lot easier on San Francisco 49ers head ...

As the San Francisco 49ers prepare for what promises to be a tough season, all eyes are on safety Talanoa Hufanga. After ...

The San Francisco 49ers will face the Los Angeles Rams on Sunday without wide receiver Deebo Samuel and running back ...

49ers GM John Lynch said Friday that Cowing "may get some [opportunities]" in Sunday's game against the Rams, Matt Barrows of The Athletic reports. With RB Christian McCaffrey (Achilles) on injured ...

An oblique injury has kept Seattle Seahawks running back Kenneth Walker III out of the lineup. He missed their Week 2 win ...

Deebo Samuel, Cooper Kupp and Isiah Pacheco were just a few ... considering the Niners' next two games are against the beat-up Rams and then the Patriots. But the 49ers themselves are already all ...

Jamey Eisenberg believes injuries to key players have set the stage for a breakout performance by Brandon Aiyuk ...

According to Tallysight, a whopping 96% of experts are picking the 49ers to beat the Rams. It’s slightly better when ...

San Francisco 49ers quarterback Brock Purdy spoke about orchestrating the team's offense without playmakers Christian ...

Greg Scholz runs through the biggest fantasy football injury worries of Week 3, leading off with A.J. Brown's precarious ...