An American Airlines plane and a U.S. Army helicopter collided near Reagan National Airport and crashed into the Potomac River, according to officials.

The number of people onboard and any fatalities is unknown at this time. The plane can carry up to 65 passengers and four crew members.

A passenger jet carrying 64 people collided Wednesday with an Army helicopter while landing at Ronald Reagan National Airport near Washington, prompting a large search-and-rescue operation in the nearby Potomac River.

An Army Black Hawk helicopter collided midair with an American Airlines flight from Wichita, Kansas, at Reagan National Airport on Wednesday.

Robert Isom, American Airlines CEO, gave a briefing Wednesday evening after an aircraft operated by one of the company's subsidiaries collided with a military helicopter and crashed into the Potomac River.

An American Airlines flight and a military helicopter collided and crashed into the Potomac River near Reagan National Airport Wednesday evening.

The American Airlines flight that crashed with 60 passengers and four crew members onboard reportedly split in half after its collision on Wednesday.

The plane, which took off from Wichita, Kan., with 64 people on board, was landing at Reagan National – traveling north toward Runway 33.

An American Airlines regional passenger jet was involved in a mid-air collision on Wednesday night with a U.S. Army Black Hawk helicopter near Reagan Washington National Airport, officials said.

The flight appeared to collide with a helicopter just before it was scheduled to land. This is a developing story and will be updated.

Wednesday night’s crash of an American Airlines commuter plane in Washington could be one of the worst disasters for the Fort Worth-based airline in more than two decades.