It's only Week 3, but both the 49ers and Rams are dealing with several key injuries entering Sunday's game. For San Francisco ...

Greg Scholz runs through the biggest fantasy football injury worries of Week 3, leading off with A.J. Brown's precarious ...

Brock Purdy plays much better with Deebo Samuel than without him. That's a fact. This Sunday, Purdy and the 49ers will have ...

Samuel (calf) has been ruled out for Sunday's game against the Rams, Matt Barrows of The Athletic reports.

Speaking to NBC Sports Bay Area's Greg Papa on "49ers Game Plan," Kyle Shanahan explained why the offense won't change ...

San Francisco 49ers' George Kittle is listed as doubtful for Sunday's game against the Rams. He joins Christian McCaffrey and ...

With Christian McCaffrey already on the injured reserve, Deebo Samuel has been ruled out due to injury for Week 3 in Los ...

Sunday’s NFC West showdown between the San Francisco 49ers and Los Angeles Rams could be an ugly affair, as both teams are ...

San Francisco 49ers head coach Kyle Shanahan joined Bay Area radio station KNBR on Thursday to provide an update on two ...

Two of the best wide receivers in the NFL are expected to be on the field for their respective Week 3 games. Justin Jefferson ...

The San Francisco 49ers will likely be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...