In a Phase I study, previously treated pediatric SMA patients exhibited reductions in a marker of neurodegeneration after salanersen treatment.

The funding will support the development of Revolution's RAS(ON) inhibitor daraxonrasib in exchange for tiered royalties on its sales.

UCLA-led investigators say additional research is needed into why guideline-recommended genetic testing remains low among ...

In a Phase I/II clinical trial, TKI-pretreated NSCLC patients given zidesamtinib had an overall response rate of 44 percent.

In the NEULARK trial, patients with early-stage LRRK2-driven Parkinson's disease will receive Neuron23's NEU-411 or a placebo.

The agency maintains that the beta-amyloid-targeting drugs show too limited benefit to justify their cost to the National Health Service.

NEW YORK – The US Food and Drug Administration on Monday approved AstraZeneca and Daiichi Sankyo's TROP2-directed antibody drug conjugate Datroway (datopotamab deruxtecan or dato-DXd) for previously ...

The funding comes from the Foundation Fighting Blindness' venture philanthropy arm, the Retinal Degeneration Fund.

Top-line results from a Phase III trial showed an overall survival benefit for zanzalintinib combo therapy in microsatellite-stable colorectal cancer.

For selected applicants, the agency plans to cut review times down to one to two months and provide "tumor board-style" ...